Population genetic and family data for the human minisatellite locus D16S309 (MS205) in Germans
- PMID: 9007632
- DOI: 10.1007/BF01225515
Population genetic and family data for the human minisatellite locus D16S309 (MS205) in Germans
Abstract
The distribution of restriction fragments at the DNA minisatellite locus D16S309 was estimated by investigating blood samples from 2617 unrelated West German Caucasians and 1269 offspring. Furthermore segregation of fragments was studied in a large family and in trios. Altogether 2296 meioses were studied, revealing 7 paternal and 3 maternal mutations. Inspection of "phenotypes" did not reveal any remarkable deviation from Hardy-Weinberg equilibrium.