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. 1977 Aug;36(4):378-80.
doi: 10.1136/ard.36.4.378.

Effect of D(-)penicillamine on chronic experimental arthritis in rabbits

I M Hunneyball, G A Stewart, D R Stanworth

Effect of D(-)penicillamine on chronic experimental arthritis in rabbits

I M Hunneyball et al. Ann Rheum Dis. 1977 Aug.

Abstract

Preliminary observations on the effect of D(-)penicillamine on chronic antigen-induced experimental arthritis in rabbits are reported. Daily oral administration of penicillamine, at a dose equivalent to that usually administered to rheumatoid arthritis patients, diminished the arthritis in 2 out of 3 animals as assessed by both measurement of joint circumference and histological examination.

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