Role REVersal: understanding how RRE RNA binds its peptide ligand
- PMID: 9016721
- DOI: 10.1016/s0969-2126(97)00161-5
Role REVersal: understanding how RRE RNA binds its peptide ligand
Abstract
The structure of a complex between the HIV Revresponsive element (RRE) RNA and a fragment of the Rev protein has recently been determined by NMR. Together with previous studies of the Tat-TAR complex, these results show how RNA elements with considerable tertiary structure are able to play a more active role in directing binding to elements of protein secondary structure.
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