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. 1997;37(1):48-52.
doi: 10.1159/000117405.

Effects of HIV seropositivity and drug abuse on cognitive function

M P Grassi  1 , C Perin, F Clerici, C Zocchetti, M Borella, A Cargnel, A Mangoni
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Effects of HIV seropositivity and drug abuse on cognitive function

M P Grassi et al. Eur Neurol. 1997.

Abstract

Fifty-eight HIV-positive drug abusers and 22 HIV-positive nondrug abusers at stages II-III and IV of the Centers for Disease Control classification were evaluated neuropsychologically. The study confirmed previous findings that drug abuse has a negative influence on cognitive function. It also emerges that seropositivity affects cognitive function, although the poor performance of group II-III patients compared to group IV may be explained by factors related to seropositivity (anxiety and panic) rather than the disease itself. It is concluded that disease-related factors probably determine cognitive performance in the earlier stages of HIV infection.

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