Comment on

• Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients.

  Porter PL, Malone KE, Heagerty PJ, Alexander GM, Gatti LA, Firpo EJ, Daling JR, Roberts JM. Porter PL, et al. Nat Med. 1997 Feb;3(2):222-5. doi: 10.1038/nm0297-222. Nat Med. 1997. PMID: 9018243
• Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer.

  Catzavelos C, Bhattacharya N, Ung YC, Wilson JA, Roncari L, Sandhu C, Shaw P, Yeger H, Morava-Protzner I, Kapusta L, Franssen E, Pritchard KI, Slingerland JM. Catzavelos C, et al. Nat Med. 1997 Feb;3(2):227-30. doi: 10.1038/nm0297-227. Nat Med. 1997. PMID: 9018244
• Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

  Loda M, Cukor B, Tam SW, Lavin P, Fiorentino M, Draetta GF, Jessup JM, Pagano M. Loda M, et al. Nat Med. 1997 Feb;3(2):231-4. doi: 10.1038/nm0297-231. Nat Med. 1997. PMID: 9018245