Comment in

• Severe persistent visual field constriction associated with vigabatrin. Chronic refractory epilepsy may have role in causing these unusual lesions.

  Wilson EA, Brodie MJ. Wilson EA, et al. BMJ. 1997 Jun 7;314(7095):1693. BMJ. 1997. PMID: 9193311 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Reaction might be dose dependent.

  Wong IC, Mawer GE, Sander JW. Wong IC, et al. BMJ. 1997 Jun 7;314(7095):1693-4. BMJ. 1997. PMID: 9193312 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Patients taking vigabatrin should have regular visual field testing.

  Blackwell N, Hayllar J, Kelly G. Blackwell N, et al. BMJ. 1997 Jun 7;314(7095):1694. BMJ. 1997. PMID: 9193313 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Four possible explanations exist.

  Harding GF. Harding GF. BMJ. 1997 Jun 7;314(7095):1694. BMJ. 1997. PMID: 9193314 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Manufacturers have started several studies.

  Backstrom JT, Hinkle RL, Flicker MR. Backstrom JT, et al. BMJ. 1997 Jun 7;314(7095):1694-5. BMJ. 1997. PMID: 9193315 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Benefit: risk ratio must be calculated for individual patients.

  Harding GF. Harding GF. BMJ. 1998 Jan 17;316(7126):232-3. BMJ. 1998. PMID: 9468716 Free PMC article. No abstract available.
• Severe persistent visual field constriction associated with vigabatrin. Asymptomatic as well as symptomatic defects occur with vigabatrin.

  Mackenzie R, Klistorner A. Mackenzie R, et al. BMJ. 1998 Jan 17;316(7126):233. BMJ. 1998. PMID: 9468717 Free PMC article. No abstract available.
• Study is needed of visual field defects associated with any long term antiepileptic drug.

  Rao GP, Fat FA, Kyle G, Leach JP, Chadwick DW, Batterbury M. Rao GP, et al. BMJ. 1998 Jul 18;317(7152):206. doi: 10.1136/bmj.317.7152.206. BMJ. 1998. PMID: 9665915 Free PMC article. No abstract available.
• Guideline may help in prescribing vigabatrin.

  Appleton RE. Appleton RE. BMJ. 1998 Nov 7;317(7168):1322. doi: 10.1136/bmj.317.7168.1322. BMJ. 1998. PMID: 9804738 Free PMC article. No abstract available.
• Infantile spasms and vigabatrin. Visual field defects may be permanent.

  Lhatoo SD, Sander JW. Lhatoo SD, et al. BMJ. 1999 Jan 2;318(7175):57. BMJ. 1999. PMID: 10068225 No abstract available.
• Guideline for prescribing vigabatrin in children has been revised. Vigabatrin Paediatric Advisory Group.

  Vigabatrin Paediatric Advisory Group. Vigabatrin Paediatric Advisory Group. BMJ. 2000 May 20;320(7246):1404-5. BMJ. 2000. PMID: 10858057 Free PMC article. No abstract available.