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Review
. 1997 Jan-Feb;41(1):98-108.
doi: 10.1159/000332313.

Laser scanning cytometry in pathology of solid tumors. A review

W Gorczyca  1 , Z Darzynkiewicz, M R Melamed
Affiliations
Review

Laser scanning cytometry in pathology of solid tumors. A review

W Gorczyca et al. Acta Cytol. 1997 Jan-Feb.

Abstract

Objective: To review application of laser scanning cytometry (LSC) to analyze several different parameters of human solid tumors in relation to the cell cycle.

Study design: Tissue sections of cytology specimens were stained for specific parameters and analyzed by LSC.

Results: Examples of LSC analysis of the expression of ER, Ki-67, cyclin B1, BrdUrd and ploidy are given.

Conclusion: LSC provides rapid, high-precision measurement of the chosen parameters or constituents of each cell in a population of cells and correlates those measurements with the visual image of the corresponding cell.

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