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Review
. 1997 Jan 13;136(1):1-4.
doi: 10.1083/jcb.136.1.1.

Anchorage-dependent cell cycle progression

Affiliations
Review

Anchorage-dependent cell cycle progression

R K Assoian. J Cell Biol. .
No abstract available

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Figures

Figure 1
Figure 1
Coordinated control of G1 phase cell cycle progression by growth factors and the extracellular matrix (ECM). A working model showing the major sites of growth factor and ECM action (solid arrows) during cell cycle progression from G0 to S phase. Cyclin E gene expression is strongly pRb/E2F dependent, but the cyclin E protein is stable and present in G1 phase cells both before and after pRb phosphorylation. Regulatory phosphorylations and the roles of INK4s are not shown.

References

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    1. Benecke B-J, Ben-Ze'ev A, Penman S. The control of mRNA production, translation and turnover in suspended and reattached anchorage-dependent fibroblasts. Cell. 1978;14:931–939. - PubMed
    1. Böhmer R-M, Scharf E, Assoian RK. Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1. Mol Biol Cell. 1996;7:101–111. - PMC - PubMed
    1. Carstens, C.-P., A. Krämer, and W.E. Fahl. 1996. Adhesion-dependent control of cyclin E/cdk2 activity and cell cycle progression in normal but not in Ha-ras transformed NRK cells. Exp. Cell Res. In press - PubMed
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