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. 1977 Aug;7(8):588-90.
doi: 10.1002/eji.1830070818.

Rat bile as a convenient source of secretory IgA and free secretory component

I Lemaître-Coelho, G D Jackson, J P Vaerman

Rat bile as a convenient source of secretory IgA and free secretory component

I Lemaître-Coelho et al. Eur J Immunol. 1977 Aug.

Abstract

Rat hepatic bile contains three proteins as major constituents: secretory IgA (SIgA), free secretory component (FSC) and albumin. Traces of alpha-macroglobulin, transferrin, IgG and IgM are also detectable. The bile duct daily pours between 5-12 mg each of SIgA and FSC into the rat duodenum. The origin and function of these proteins in bile may represent important clues in the understanding of the SIgA system.

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