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. 1997 Mar;71(3):2567-71.
doi: 10.1128/JVI.71.3.2567-2571.1997.

Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells

A H Koyama  1 , Y Miwa
Affiliations

Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells

A H Koyama et al. J Virol. 1997 Mar.

Abstract

HEp-2 cells underwent apoptosis when the cells were incubated in medium containing sorbitol. Infection with herpes simplex virus type 1 (HSV-1) prior to the sorbitol treatment suppressed this apoptosis completely, indicating that HSV-1 carries an antiapoptosis gene. In addition, HSV-1 multiplication was restricted in these apoptotic HEp-2 cells.

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References

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