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Review
. 1979 Feb 9;23(3):131-41.
doi: 10.1007/BF00219452.

Staphylococcal nuclease reviewed: a prototypic study in contemporary enzymology. IV. The nuclease as a model for protein folding

P W Tucker, E E Hazen Jr, F A Cotton
Review

Staphylococcal nuclease reviewed: a prototypic study in contemporary enzymology. IV. The nuclease as a model for protein folding

P W Tucker et al. Mol Cell Biochem. .

Abstract

This is the last in a series of four articles in which the chemical, enzymological and crystallographic work on Ribonucleate (deoxyribonucleate)-3'-nucleotidohydrolase, EC 3.1.4.4 (staphylococcal nuclease, micrococcal nuclease) will be reviewed and correlated. This article discusses the use of the nuclease as a model system for the study of the mechanisms and energetics of the folding-unfolding reaction in proteins and for the study of the interrelationships between amino acid sequence and three-dimensional structure.

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References

    1. J Am Chem Soc. 1969 Mar 26;91(7):1812-6 - PubMed
    1. Nature. 1974 Sep 20;251(5472):242-4 - PubMed
    1. Adv Protein Chem. 1970;24:1-95 - PubMed
    1. J Biol Chem. 1971 Dec 10;246(23):7392-7 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1972;36:257-61 - PubMed

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