Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Oct;24(1):401-5.
doi: 10.1128/JVI.24.1.401-405.1977.

Phosphorylated protein component present in influenza virions

M L Privalsky, E E Penhoet

Phosphorylated protein component present in influenza virions

M L Privalsky et al. J Virol. 1977 Oct.

Abstract

The nucleoprotein of the WSN strain of influenza was found to be phosphorylated in vitro. The phosphate-protein bond was stable to hot trichloroacetic acid, RNase, DNase, succinic acid, and succinic acid-hydroxylamine, but sensitive to hydrolysis by bacterial alkaline phosphatase. This suggested that the nucleoprotein is in the form of a phosphomonoester. Acid hydrolysis of the isolated nucleoprotein followed by thin-layer electrophoresis identified the phosphorylated amino acid residue as phosphoserine.

PubMed Disclaimer

References

    1. J Biol Chem. 1962 Mar;237:841-6 - PubMed
    1. J Virol. 1972 Oct;10(4):689-97 - PubMed
    1. Nat New Biol. 1971 Sep 29;233(39):137-40 - PubMed
    1. Virology. 1973 Mar;52(1):246-63 - PubMed
    1. Virology. 1972 Feb;47(2):536-8 - PubMed

Publication types

LinkOut - more resources