Review
doi: 10.1016/s0968-0004(96)20033-7.
Aminoacyl-tRNA synthesis: divergent routes to a common goal
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- PMID: 9048478
- DOI: 10.1016/s0968-0004(96)20033-7
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Review
Aminoacyl-tRNA synthesis: divergent routes to a common goal
Trends Biochem Sci.
1997 Feb.
Free article
Abstract
Aminoacyl-tRNAs are key components in protein synthesis. They are formed directly by correct acylation of tRNA (by aminoacyl-tRNA synthetases) or indirectly by tRNA-dependent transformation of misacylated tRNAs. The accuracy of aminoacyl-tRNA synthesis is enhanced by a number of further protein-RNA or protein-protein interactions, some of which are restricted to Archaea, and might reflect adaptation mechanisms to diverse conditions.
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