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Review
. 1997 Feb;84(2):160-6.

Matrix metalloproteinases

S L Parsons  1 , S A Watson, P D Brown, H M Collins, R J Steele
Affiliations
  • PMID: 9052425
Review

Matrix metalloproteinases

S L Parsons et al. Br J Surg. 1997 Feb.

Abstract

Background: The matrix metalloproteinases (MMPs) have a role in gastrointestinal malignancy. This role is reviewed, with particular reference to the gelatinase subgroup of enzymes.

Methods: All relevant papers derived from the Medline and Enbase databases between 1984 and early 1996 were reviewed.

Result and conclusion: There is now strong evidence that MMPs play a major role in tumour invasion and metastasis. The development of MMP inhibitors may lead to important new treatment for the control of malignant disease.

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Comment in

  • Matrix metalloproteinases.
    Roy MK, Carey PD. Roy MK, et al. Br J Surg. 1997 Aug;84(8):1171. doi: 10.1002/bjs.1800840842. Br J Surg. 1997. PMID: 9278677 No abstract available.

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