[Study of glucose tolerance disorder in women with a complicated obstetrical anamnesis]

Abstract

The authors examined selectively 849 women with complicated obstetrical anamnesis in the past and at random 636 women with the aid of the glucose tolerance test (GTT). The incidence of pathological GTT among women with various types of pathology of pregnancy (24%) was greater than in the control group (16.9%). Diabetes mellitus was revealed in 7.8 and 5.1% of cases, respectively. Some types of pathology of pregnancy were of particular significance in the development of the prediabetic state. A high incidence of GTT of diabetic type was noted in women with perinatal death of the fetus (13.1%) and the neonate (11.8%), in women with a large fetus in combination with other types of pathology of pregnancy (12.6%), and also among women who had delivered three and more large fetuses in the past (19.5%). The incidence of diabetic GTT increased in older and obese women; in marked excess of body weight the percentage of GTT of diabetic type was about the same in all the women under study. Among the women with pathology of pregnancy adiposity developed more frequently and in younger persons, and the excess of body weight was much greater in comparison with the control group. The authors consider that GTT should be conducted in all the women with the mentioned pathology of pregnancy in the anamnesis for the purpose of early detection of diabetes mellitus and also for perinatal fetal protection.