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Comparative Study
. 1997 Mar;41(3):709-11.
doi: 10.1128/AAC.41.3.709.

Comparison of the in vitro activities of Bay 12-8039, a new quinolone, and other antimicrobials against clinically important anaerobes

K E Aldridge  1 , D S Ashcraft
Affiliations
Comparative Study

Comparison of the in vitro activities of Bay 12-8039, a new quinolone, and other antimicrobials against clinically important anaerobes

K E Aldridge et al. Antimicrob Agents Chemother. 1997 Mar.

Abstract

Bay 12-8039, a new 8-methoxy quinolone, was compared with other agents for activity against clinically relevant anaerobes. Bay 12-8039 inhibited 91 and 96% of the 410 test isolates at 2 and 4 micrograms/ml, respectively. Bay 12-8039 had activity comparable to that metronidazole and overall was at least 16-fold more active than ciprofloxacin, ofloxacin, and cefoxitin, 32-fold more active than cefotetan, and at least 128-fold more active than penicillin G.

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References

    1. Diagn Microbiol Infect Dis. 1994 Apr;18(4):235-41 - PubMed
    1. Antimicrob Agents Chemother. 1994 Oct;38(10):2504-9 - PubMed
    1. Antimicrob Agents Chemother. 1982 Oct;22(4):579-84 - PubMed
    1. Clin Infect Dis. 1994 Feb;18(2):260-1 - PubMed
    1. Scand J Infect Dis Suppl. 1985;46:57-63 - PubMed

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