Possible contributions of magnocellular- and parvocellular-pathway cells to transient VEPs

Abstract

We have measured transient visual evoked potentials (VEPs) to low-contrast luminance stimuli favoring responses of magnocellular pathway cells and to low-contrast red-green stimuli favoring parvocellular cells. Stimuli were square-wave alternating, 3-deg homogeneous disks. Low-contrast stimuli modulated in luminance elicited relatively simple responses. For some observers, a negativity was present that saturated at low contrast. This may be the signature of inputs from magnocellular channels to the visual cortex. The slope of the contrast-response curve for low-contrast stimuli was about the same for all subjects. For medium contrasts, these contrast-response curves displayed an abrupt increase of slope. The shallower slope may reflect the responsivity of magnocellular-pathway inputs to the cortex, whereas the steeper slope may be caused by additional parvocellular activation. Contrast-response curves for the most sensitive waveforms of the isoluminant green-red modulation also showed two branches, although not as clearly as for luminance. This may indicate parvocellular-mediated activity for small chromatic differences, and a combination of parvocellular and magnocellular inputs for larger contrasts. Curves of time-to-peak response as a function of contrast often changed their monotonous behavior near the kink of the corresponding contrast-response curve, thus supporting the notion of a contribution from several mechanisms to the main waveforms.