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Review
. 1997 Feb:155:145-54.
doi: 10.1111/j.1600-065x.1997.tb00947.x.

Arousal and inhibition of human NK cells

L L Lanier  1 , B Corliss, J H Phillips
Affiliations
Review

Arousal and inhibition of human NK cells

L L Lanier et al. Immunol Rev. 1997 Feb.

Abstract

NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regulation of these responses by the killer cell inhibitory (KIR) receptors.

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