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Review
. 1997 Feb;24(4):471-5.

[p53 mutation does not determine prognosis in non-Hodgkin's lymphoma]

[Article in Japanese]
M Osada  1 , C Ishioka, Y Murakawa, R Ichinohasama, R Kanamaru, S Ikawa
Affiliations
  • PMID: 9063486
Review

[p53 mutation does not determine prognosis in non-Hodgkin's lymphoma]

[Article in Japanese]
M Osada et al. Gan To Kagaku Ryoho. 1997 Feb.

Abstract

We studied the clinical significance of the extent of p53 protein expression by immunohistochemical analysis and p53 mutations by functional analysis of p53 in 42 patients with high and intermediate grade of Non-Hodgkin's Lymphoma (NHL). Neither p53 expression nor mutation correlated with short survival or resistance to chemoradiotherapy, implying that p53 mutation is not a prognostic factor in NHL.

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