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. 1977 May-Jun:(3):279-84.

[Detection of DNA in the composition of influenza virus]

[Article in Russian]
E N Kantorovich-Prokudina, N P Semenova, O N Berezina, V M Zhdanov
  • PMID: 906439

[Detection of DNA in the composition of influenza virus]

[Article in Russian]
E N Kantorovich-Prokudina et al. Vopr Virusol. 1977 May-Jun.

Abstract

When influenza virus multiplies in chick embryos, incorporation of 3H-thymidine into virus particles is observed. The radioactivity is localized in influenza virus nucleoprotein. The analysis of 3H-thymidine-containing structures in cesium chloride density gradient permits to qualify them as DNA. Isodensity centrifugation of in vitro 125I-labeled preparation of nucleic acid from influenza virus in cesium sulphate gradient also reveals DNA molecules, in addition to RNA. A high hybridization rate of influenza virus 125I-DNA with virion RNA has been demonstrated.

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