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Review
. 1997 Mar;13(3):105-10.
doi: 10.1016/s0168-9525(97)01006-8.

The JAK-STAT pathway in Drosophila

X S Hou  1 , N Perrimon
Affiliations
Review

The JAK-STAT pathway in Drosophila

X S Hou et al. Trends Genet. 1997 Mar.

Abstract

Recent studies in Drosophila have identified a single JAK and a single STAT protein. Genetic and biochemical analyses reveal that these two proteins operate in the same signal transduction pathway. Phenotypic analyses of JAK and STAT mutants implicate this pathway in a number of developmental decisions, in particular the regulation of pair-rule genes and fly hematopoiesis.

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