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. 1997 Mar;42(2):152-62.
doi: 10.1177/070674379704200205.

The history of the psychopharmacology of schizophrenia

H E Lehmann  1 , T A Ban
Affiliations

The history of the psychopharmacology of schizophrenia

H E Lehmann et al. Can J Psychiatry. 1997 Mar.

Abstract

Objective: To review the historical development of the psychopharmacological treatment of schizophrenia.

Method: A chronological literature review of the clinical practices and theoretical models that have controlled drug treatment of schizophrenia at different times.

Results: Effective treatment of schizophrenia was achieved only after the introduction of antipsychotic drugs, in the 1950s, and is still progressing.

Conclusion: Close collaboration between basic neuroscience and careful and informed clinical practice are likely to lead to continued progress.

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