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Review
. 1996 Dec;53(4):290-3.

Drug efflux as a mechanism of resistance

Affiliations
  • PMID: 9069107
Review

Drug efflux as a mechanism of resistance

J B Williams. Br J Biomed Sci. 1996 Dec.

Abstract

A review of efflux as a mechanism of antibiotic resistance in both bacterial and eukaryotic cells is presented. This covers membrane transport, the evolution of efflux transporters, their genetic control and classification into families, and an appreciation of the widespread distribution and occurrence of these mechanisms in nature.

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