Review
doi: 10.1016/s1074-5521(97)90232-5.
Nef and PAK: virulence factor and cellular accomplice
Affiliations
- PMID: 9070423
- DOI: 10.1016/s1074-5521(97)90232-5
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Review
Nef and PAK: virulence factor and cellular accomplice
Chem Biol.
1997 Jan.
Abstract
The Nef protein is important in HIV replication and in AIDS pathogenesis. The finding that Nef activates a member of the PAK family of protein kinases provides new insights into the mechanisms of action of this critical virulence factor.
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