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. 1977 Sep;12(3):423-6.
doi: 10.1128/AAC.12.3.423.

Elimination of plasmids from several bacterial species by novobiocin

Elimination of plasmids from several bacterial species by novobiocin

G L McHugh et al. Antimicrob Agents Chemother. 1977 Sep.

Abstract

Certain plasmids can be eliminated by exposure to growth-inhibiting concentrations of novobiocin. Novobiocin cured 8 of 14 plasmids (13 R-plasmids and an F' lac) among one or another of four different bacterial hosts.

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