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Comparative Study
. 1977 Sep;12(3):442-3.
doi: 10.1128/AAC.12.3.442.

In vitro activity of cefaclor, a new orally administered cephalosporin antibiotic

J Santoro, M E Levison
Comparative Study

In vitro activity of cefaclor, a new orally administered cephalosporin antibiotic

J Santoro et al. Antimicrob Agents Chemother. 1977 Sep.

Abstract

The in vitro antibacterial activity of cefaclor, cephalothin, and cephalexin against 261 clinical isolates of Staphylococcus aureus and Enterobacteriaceae was compared. Cefaclor and cephalexin were about equally active against S. aureus. Cefaclor was the most active cephalosporin against Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae. The effect on the antimicrobial activity using a relatively high and low inoculum was pronounced for cefaclor when compared with that of cephalothin.

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References

    1. Antimicrob Agents Chemother. 1977 Mar;11(3):470-4 - PubMed

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