. 1997:31 Suppl 2:14-9; discussion 24-7.
doi: 10.1159/000474543.
Antiandrogen monotherapy in the management of advanced prostate cancer
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- PMID: 9074906
- DOI: 10.1159/000474543
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Antiandrogen monotherapy in the management of advanced prostate cancer
Eur Urol.
1997.
Abstract
The utility of monotherapy with antiandrogens in prostate cancer is under investigation. Flutamide (Eulexin, Schering-Plough International) appears equally effective to castration in prolonging progression-free survival. Nilutamide (Anandron, Roussel) has been studied less widely, but may represent a valid treatment option in advanced prostate cancer. Preliminary results suggest that bicalutamide (Casodex, Zeneca Ltd) is as effective as castration in non-metastatic disease. Monotherapy with non-steroidal antiandrogens may offer successful palliative management of advanced prostate cancer with significant value in enhancing certain aspects of quality of life.
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