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. 1997 Mar;7(3):210-22.
doi: 10.1101/gr.7.3.210.

X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content

R Nagaraja  1 , S MacMillan, J Kere, C Jones, S Griffin, M Schmatz, J Terrell, M Shomaker, C Jermak, C Hott, M Masisi, S Mumm, A Srivastava, G Pilia, T Featherstone, R Mazzarella, S Kesterson, B McCauley, B Railey, F Burough, V Nowotny, M D'Urso, D States, B Brownstein, D Schlessinger
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Free article

X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content

R Nagaraja et al. Genome Res. 1997 Mar.
Free article

Abstract

A YAC/STS map of the X chromosome has reached an inter-STS resolution of 75 kb. The map density is sufficient to provide YACs or other large-insert clones that are cross-validated as sequencing substrates across the chromosome. Marker density also permits estimates of regional gene content and a detailed comparison of genetic and physical map distances. Five regions are detected with relatively high G + C, correlated with gene richness; and a 17-Mb region with very low recombination is revealed between the Xq13.3 [XIST] and Xq21.3 XY homology loci.

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