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Review
. 1997 Mar;5(3):109-14.
doi: 10.1016/S0966-842X(97)01000-7.

Interactions between enteropathogenic Escherichia coli and host epithelial cells

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Review

Interactions between enteropathogenic Escherichia coli and host epithelial cells

M S Donnenberg et al. Trends Microbiol. 1997 Mar.

Abstract

The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type III secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.

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