[Value of computer-assisted sperm analysis (CASA). Reproducibility--online documentation--prognostic value]

Abstract

Computer-Assisted Semen Analysis (CASA) permits a determination of sperm count and sperm motility, improves reproducibility and facilitates the documentation of the results. In addition, new motility parameters can be measured. An analysis of the CASA parameters of 792 ejaculates revealed that their distribution is similar to that of the sperm count and sperm motility obtained by simple microscopic counting. A comparison of CASA parameters with the subsequent conception rate with the aid of Cox's regression analysis, showed that sperm count and total motility are the sole predictors of fertility. Attempts to measure sperm morphology using CASA have already been initiated. It can be noted that CASA analysis is superior to the simple microscopic evaluation of the ejaculate in its objectivity, reproducibility and on-line documentation. However, it does not increase the significance of semen analysis in terms of fertility prognosis.