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. 1977 Oct;101(4):1343-5.
doi: 10.1210/endo-101-4-1343.

Dopamine enhances the action of prolactin on rat blood vessels. Implications for dopamine effects on plasma prolactin

M S Manku, D F Horrobin, H Zinner, M Karmazyn, R O Morgan, A I Ally, R A Karmali

Dopamine enhances the action of prolactin on rat blood vessels. Implications for dopamine effects on plasma prolactin

M S Manku et al. Endocrinology. 1977 Oct.

Abstract

It has been claimed that dopamine enhances peripheral uptake of prolactin. Dopamine at 2.1 x 10(-9)M, a concentration which had no effect by itself, enhanced both the potentiation of rat mesenteric vascular reactivity caused by 50ng/ml ovine prolactin and the inhibition of reactivity caused by 500ng/ml prolactin. These observations are consistent with the proposal that dopamine can interact peripherally with prolactin.

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