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. 1977 Oct 15;33(10):1394-6.
doi: 10.1007/BF01920202.

Adrenalectomy, ovarian HCG-binding and the onset of female puberty in the rat

J W Siebers, W Engel

Adrenalectomy, ovarian HCG-binding and the onset of female puberty in the rat

J W Siebers et al. Experientia. .

Abstract

The delay of puberty onset in female rats adrenalectomized before the 25th day of age is due neither to changes in the number of ovarian HCG-receptors nor to an altered hormone affinity of these receptors. It is assumed that glucocorticoids act on an intracellular level in the ovarian cells, possibly by alterations of cyclic AMP-dependent phosphodiesterase activity.

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References

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    1. Nature. 1974 Sep 13;251(5471):146-8 - PubMed
    1. Steroids. 1973 Nov;22(5):597-608 - PubMed

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