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. 1996 Dec;20(6):385-93.
doi: 10.1007/BF02257282.

Optimum investments in project evaluations: when are cost-effectiveness analyses cost-effective?

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Optimum investments in project evaluations: when are cost-effectiveness analyses cost-effective?

R S Woodward et al. J Med Syst. 1996 Dec.

Abstract

This manuscript extends the classical models of the value of information to ask whether a hospital's net financial return is ever maximized by a cost-effectiveness analysis of retrospective data when watchful waiting and a full randomized clinical trial are alternative methodologies. The manuscript demonstrates that (1) some small-scale retrospective analyses may negatively affect net income and (2) under some conditions, larger-scale retrospective analyses may maximize net income. The manuscript also suggests that risk aversion increases the value of information and therefore the optimum expenditure on a project evaluation.

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