Endometriosis is not detrimental to embryo implantation in oocyte recipients
- PMID: 9090558
- PMCID: PMC3454677
- DOI: 10.1007/BF02766132
Endometriosis is not detrimental to embryo implantation in oocyte recipients
Abstract
Purpose: Our purpose was to determine the effects of endometriosis on implantation and pregnancy rates in ovum recipients.
Methods: The medical records of 239 consecutive oocyte recipient patients who were treated between January 1, 1991, and June 30, 1995, were analyzed retrospectively. Recipients with endometriosis (group 1; n = 55) were compared to recipients without endometriosis (group II; n = 184). Patients in group I had active endometriotic disease confirmed by laparoscopy and were subdivided into mild (Stages I and II; n = 18) and moderate to severe (Stages III and IV; n = 37) endometriosis.
Results: No difference was found in recipient age, endometrial thickness, donor age, and embryos transferred. The pregnancy rates (28 versus 29%) and implantation rates (12 and 13%) were also comparable between group I and group II, as well as between patients with mild and patients with moderate to severe endometriosis.
Conclusions: The presence of endometriosis in oocyte recipients does not lower implantation or pregnancy rates. We conclude that the adverse effect of endometriosis on reproductive outcome is not related to implantation but, in fact, is most likely an effect on oocyte or embryo quality.
References
-
- Sampson JA. Peritoneal endometriosis due to dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol. 1927;14:422–469.
-
- Damewood MD. Endometriosis and infertility: physiologic mechanisms and contemporary therapeutic considerations, including GnRH agonists. Semin Reprod Endocrinol. 1993;11:125–35. doi: 10.1055/s-2007-1018825. - DOI
-
- Mills MS, Eddowes HA, Cahill DJ, Fahy UM, Abuzeid MIM, McDermott A, Hull MGR. A prospective controlled study of in vitro fertilization, gamete intra-fallopian transfer and intrauterine insemination combined with superovulation. Hum Reprod. 1992;7:490–494. - PubMed
-
- Matson PL, Yovich JL. The treatment of infertility-associated with endometriosis by in vitro fertilization. Fertil Steril. 1986;46:432–434. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical