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. 1997 May;71(5):4103-6.
doi: 10.1128/JVI.71.5.4103-4106.1997.

Latent herpes simplex virus type 1 gene expression in ganglia innervating the human gastrointestinal tract

R M Gesser  1 , S C Koo
Affiliations

Latent herpes simplex virus type 1 gene expression in ganglia innervating the human gastrointestinal tract

R M Gesser et al. J Virol. 1997 May.

Abstract

Using in situ hybridization, we demonstrated that latent herpes simplex virus type 1 (HSV-1) gene expression is prevalent in human adult nodose ganglia. This suggests that infection of gastrointestinal sensory nerves, probably through swallowed virus-laden oral secretions, occurs commonly and that HSV-1 reactivating from this site may play a role in recurrent gastrointestinal disorders.

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