Nucleotide sequences of 5'-terminal ribosome-protected initiation regions from two reovirus messages

Abstract

Sequences for two reovirus ribosome-protected fragments are presented. Comparison with four other reovirus initiation sites reveals only two common features: the 5'-terminal sequence m7GpppGmCUA, and (located 15-33 nucleotides from the cap) the sequence AUGG. Both the cap and the AUG codon are included in the 40S-ribosome protected region from all six reovirus messages.