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. 1997 Apr 1;94(7):2776-8.
doi: 10.1073/pnas.94.7.2776.

The cell cycle and cancer

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The cell cycle and cancer

K Collins et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figure 1
Figure 1
A schematic representation of the mammalian cell cycle. In each cell division cycle, chromosomes are replicated once (DNA synthesis or S-phase) and segregated to create two genetically identical daughter cells (mitosis or M-phase). These events are spaced by intervals of growth and reorganization (gap phases G1 and G2). Cells can stop cycling after division, entering a state of quiescence (G0). Commitment to traverse an entire cycle is made in late G1. Progress through the cycle is accomplished in part by the regulated activity of numerous CDK–cyclin complexes, indicated here and described in the text.

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