Leukemogenesis by Moloney murine leukemia virus: a multistep process
- PMID: 9108934
- DOI: 10.1016/S0966-842X(96)10076-7
Leukemogenesis by Moloney murine leukemia virus: a multistep process
Abstract
Moloney murine leukemia virus is a prototypical simple retrovirus that has been an extremely useful model for leukemogenesis. Important steps in leukemogenesis include proviral activation of cellular proto-oncogenes, generation of mink cell focus-inducing recombinants, and early (preleukemic) virus-induced changes in hematopoiesis.
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