Differential expression of bcl-2 and bcl-x during chicken spermatogenesis
- PMID: 9110311
- DOI: 10.1002/(SICI)1098-2795(199705)47:1<26::AID-MRD4>3.0.CO;2-S
Differential expression of bcl-2 and bcl-x during chicken spermatogenesis
Abstract
We report the isolation and characterization of a chicken testis bcl-XL cDNA coding for a long bcl-x protein with a hydrophobic tail, and the expression of bcl-2 and bcl-x during chicken spermatogenesis. Bcl-2 is highly expressed in embryonic and immature testes enriched in spermatogonia and barely detectable in mature testes, where most of the cells are meiotic and postmeiotic. Bcl-x is expressed in both mature and immature testes, but in a lesser amount in mature testes. Differential expression of bcl-2 and bcl-x during spermatogenesis is consistent with the reported different susceptibility to apoptosis of spermatogonia, and meiotic and postmeiotic cells.
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