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Clinical Trial
. 1997 Apr;104(4):623-31.
doi: 10.1016/s0161-6420(97)30261-9.

A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen

H L Little  1 , J M Showman, B W Brown
Affiliations
Clinical Trial

A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen

H L Little et al. Ophthalmology. 1997 Apr.

Abstract

Purpose: The authors determined the effect of photocoagulation of drusen on visual acuity and progression to subretinal neovascular membranes (SRNV).

Methods: One of paired eyes was randomized to photocoagulation with other eye to control in 27 patients having symmetrical maculopathy and visual acuities, aged 46 to 81 years (mean, 69.7 years); follow-up 1 to 6 years (mean, 3.2 years).

Results: Final visual acuity was improved in treated eye or decreased in control eye in 12 patients, equal in 13 patients, and decreased in treated eye in 2 patients (P < 0.006). Progression to SRNV was less with treatment.

Conclusion: Laser photocoagulation of confluent soft macular drusen may improve long-term visual prognosis.

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