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Review
. 1997 May 1;7(5):R305-7.
doi: 10.1016/s0960-9822(06)00144-8.

DNA methylation: a molecular lock

Z Siegfried  1 , H Cedar
Affiliations
Free article
Review

DNA methylation: a molecular lock

Z Siegfried et al. Curr Biol. .
Free article

Abstract

In mammals, the promoters of expressed genes are generally unmethylated, whereas those of genes that are not expressed are methylated. Two recent papers help to explain the mechanism by which methylation modulates gene expression.

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