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. 1977 Aug;36(2):276-80.
doi: 10.1038/bjc.1977.187.

A combination of chlorambucil, vinblastine, procarbazine and prednisolone for treatment of Hodgkin's disease

T J McElwain, J Toy, E Smith, M J Peckham, D E Austin
Free PMC article

A combination of chlorambucil, vinblastine, procarbazine and prednisolone for treatment of Hodgkin's disease

T J McElwain et al. Br J Cancer. 1977 Aug.
Free PMC article

Abstract

Seventy patients with Hodgkin's disease have been treated with a combination of chlorambucil, vinblastine, procarbazine and prednisolone (Ch1VPP). The complete remission rate of 75-7% compares well with that produced by other combinations. The combination is non-toxic, easily administered and can be given safely to outpatients. Its main advantage is that it is far less upsetting to patients than combinations containing nitrogen mustard.

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