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Review
. 1996 Dec;5(4):417-21.
doi: 10.1006/neur.1996.0056.

Structural correlates of cognition in dementia: quantification and assessment of synapse change

S T DeKosky  1 , S W Scheff, S D Styren
Affiliations
Review

Structural correlates of cognition in dementia: quantification and assessment of synapse change

S T DeKosky et al. Neurodegeneration. 1996 Dec.

Abstract

Dementia results from a combination of structural and neurochemical pathologies. The most reliable index of cognition in both postmortem and biopsied AD brain is synapse loss.

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