The Alzheimer family of diseases: many etiologies, one pathogenesis?
- PMID: 9122152
- PMCID: PMC33655
- DOI: 10.1073/pnas.94.6.2095
The Alzheimer family of diseases: many etiologies, one pathogenesis?
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The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue.Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):2025-30. doi: 10.1073/pnas.94.5.2025. Proc Natl Acad Sci U S A. 1997. PMID: 9050898 Free PMC article.
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