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Case Reports
. 1997 Mar;25(1-2):163-8.
doi: 10.3109/10428199709042506.

The 17p-syndrome: a distinct myelodysplastic syndrome entity?

L Jary  1 , H Mossafa, C Fourcade, P Genet, M Pulik, G Flandrin
Affiliations
Case Reports

The 17p-syndrome: a distinct myelodysplastic syndrome entity?

L Jary et al. Leuk Lymphoma. 1997 Mar.

Abstract

The 17p- syndrome is a subset of myelodysplastic syndrome characterized by "typical" dysgranulopoïesis, combining a pseudo-Pelger-Hüet and a deletion of the short arm of chromosome 17. We describe two patients; one with de novo myelodysplastic syndrome (RAEB), one with secondary MDS (RAEB-T). Both showed a 17p- deletion resulting from tanslocations involving 17p associated with an additional complex cytogenetics, and both of them had a particular type of dysgranulopoiesis, combining pseudo-Pelger-Hüet anomaly.

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