[Treatment of nasal polyposis with systemic and local corticoids]

Abstract

Surgical or medical treatment of nasal polyposis still is a challenge in otorhinolaryngology. A study was made of the effectiveness of combined local and systemic, steroid treatment. Thirty-seven patients with different grades of nasal polyposis received a combination of systemic (methylprednisolone oral 10 days) and local (inhaled budesonide, day 8 to day 28) steroids. Therapeutic effects were measured using nasal endoscopy with a four-stage system for grading nasal fossa involvement and a symptomatic scale of none, mild, moderate, and severe. The mean endoscopic score decreased from 1.14 on day 1 to 0.14 on day 28 and the symptom score from 2.8 to 1.2. The results show than nasal polyposis can be treated successfully with combined local and systemic steroid treatment.