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Comparative Study
. 1996 Mar;19(1):33-40.
doi: 10.1016/0920-9964(95)00045-3.

Family history of autoimmune diseases in psychosis

C M Gilvarry  1 , P C Sham, P B Jones, M Cannon, P Wright, S W Lewis, P Bebbington, B K Toone, R M Murray
Affiliations
Comparative Study

Family history of autoimmune diseases in psychosis

C M Gilvarry et al. Schizophr Res. 1996 Mar.

Abstract

The mothers of 101 psychotic patients and 116 normal controls were interviewed using a semi-structured questionnaire designed to determine the presence or absence of autoimmune disorders in first degree relatives of the probands. Thyrotoxicosis and insulin-dependent diabetes mellitus were significantly more common in the relatives of the psychotic patients than in the control relatives; in particular thyrotoxicosis was more frequent in the mothers of patients (11%) than the mothers of controls (2.6%). None of the examined characteristics of the patients, including RDC-diagnosis, family history of psychosis, age at onset of psychosis and winter birth, was predictive of thyrotoxicosis and insulin-dependent diabetes mellitus in relatives.

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