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. 1997 Mar;36(2):36-41.

[123I-alpha-methyltyrosine scintigraphy in malignant melanoma]

[Article in German]
H Steinert  1 , R Böni, R A Huch-Böni, R Capaul, G K von Schulthess, G Westera
Affiliations
  • PMID: 9148271

[123I-alpha-methyltyrosine scintigraphy in malignant melanoma]

[Article in German]
H Steinert et al. Nuklearmedizin. 1997 Mar.

Abstract

Aim: The aim of the study was to evaluate the ranking of the scintigraphy with L-3-123I-alpha-methyltyrosine (123I-AMT) in metastasized melanoma.

Methods: 26 metastases and one primary tumor of a malignant melanoma in six patients were examined with 123I-AMT whole-body scintigraphy and SPECT. Positron Emission Tomography with 2-18F-fluoro-2-desoxy-D-glucose (18F-FDG) was used as the golden standard.

Results: With 123I-AMT-SPECT 8/10 metastases in the thorax > 1.6 cm were detected (ratio T/NT 1.2-1.8), metastases < 1.6 cm were not detectable with SPECT. In 123I-AMT whole-body scintigraphy not one lesion showed a positive tumor uptake.

Conclusion: In single cases 123I-AMT scintigraphy can be helpful in staging of malignant melanoma.

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