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Review
. 1997 Apr;22(4):118-23.
doi: 10.1016/s0968-0004(97)01020-7.

ATP-dependent proteases that also chaperone protein biogenesis

C K Suzuki  1 , M Rep, J M van Dijl, K Suda, L A Grivell, G Schatz
Affiliations
Review

ATP-dependent proteases that also chaperone protein biogenesis

C K Suzuki et al. Trends Biochem Sci. 1997 Apr.

Abstract

The ATP-dependent proteases Clp and FtsH from bacteria, as well as mitochondrial homologs of FtsH and Lon from yeast, may act as chaperones; they mediate not only proteolysis, but also the insertion of proteins into membranes and the disassembly or oligomerization of protein complexes. The coordination of such processes with selective proteolysis may function in the quality control of protein biogenesis.

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