Extraosseous calcifying epithelial odontogenic tumor: report of two cases and review of the literature

Abstract

In this study two additional cases of extraosseous calcifying epithelial odontogenic tumor are reported, both of which exhibited a prominent clear cell component. The clinical and histopathologic findings of these two cases are compared with those of the nine reported cases from the English language literature. The age range for the 11 cases was 12 to 64 years with a mean age of 34.4 years at the time of diagnosis. Six of the tumors involved female patients and five involved male patients. Seven cases were located on the mandibular gingiva with the remaining four cases involving the maxillary gingiva. On microscopic evaluation, six of the lesions exhibited a predominant clear cell component. Appropriate management of the extraosseous calcifying epithelial odontogenic tumor consists of simple excision. No recurrences have been recorded.